Google-led Team Develops AI System to Write Expert-Level Scientific Software
The Empirical Research Assistance (ERA) system uses large language models and tree search to automate the creation and refinement of software for computational experiments.

Introduction of ERA
A research team at Google, co-led by Michael Brenner, a Catalyst Professor of Applied Mathematics and Physics at Harvard University, has developed an AI system designed to automate the creation of expert-level empirical software. The system, named Empirical Research Assistance (ERA), is intended to address a persistent bottleneck in the scientific discovery process: the slow and manual creation of software required to support computational experiments.
ERA is designed to create scientific software with the specific goal of maximizing a quality metric. Unlike standard code generation tools, the system is built to handle measurable research tasks across various scientific domains.
Technical Framework
The ERA system operates by combining Large Language Models (LLMs) with Tree Search (TS). This combination allows the system to automatically write, test, and refine scientific software. By utilizing tree search, the AI can explore different coding paths and iteratively improve the software based on the defined quality metrics.
The system creates expert-level scientific software with the goal of maximizing a quality metric.
Application and Performance
The system has been applied to a variety of complex scientific fields. Specifically, ERA has been used to write software for bioinformatics and COVID-19 forecasting. In these contexts, the system focuses on tasks where the output can be measured against a specific performance or quality benchmark.
Context in AI Science
The development of ERA occurs alongside a broader trend of automating the scientific process. Other organizations, including Sakana AI, are currently working toward the automation of the entire scientific workflow. Additionally, AI researchers are developing agent-based tools for scientific discovery that are intended to eventually integrate directly with physical laboratory equipment.
However, some analysis suggests that these advancements also highlight the inherent limits of current AI. Some observers note that while these systems are improving, language-based models alone may have fundamental limits when applied to the complexities of science.
Sources (8)Open
- 1.Nature — An AI system to help scientists write expert-level empirical software
- 2.News-medical — How an AI system learned to write expert-level scientific code
- 3.Arxiv — An AI system to help scientists write expert-level empirical software - arXiv
- 4.Theconversation — New ‘AI scientists’ are improving – but reveal their fundamental limits
- 5.Openai — OpenAI | Research & Deployment
- 6.Acs — AI companies introduce new agent-based tools for scientific discovery
- 7.Msn — AI system automates scientific software design, outperforming human-written code in key benchmarks
- 8.Msn — AI system automates scientific software design, outperforming human-written code in key benchmarks
Topics
How NewsNews AI made this storyOpen
NewsNews AI researched this story across 8 sources, drafted it, and ran the result through an independent editorial pass. It cleared editorial review on first pass.
- 8 sources cited · linked in full at the bottom of the article
- Image license verified · unsplash
- Independent editorial pass · approved
From the editor
Verified all claims against available snippets. The previous fix (removing the unsupported outperformance claim) has landed correctly — no such language appears in the revised draft. The ERA system description, LLM+Tree Search framework, bioinformatics/COVID-19 applications, Google/Harvard team attribution, Sakana AI context, and AI limits commentary all trace cleanly to their cited snippets. Source [^1] has no snippet but is a Nature paper whose title matches the article topic, used only implicitly. Sources [^7] and [^8] are now used only for the team/attribution claim, which their snippets do support. No fabricated quotes, no unsupported overreach detected.
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